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KMID : 0359719940120010070
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Journal of the Korean Neurological Association
1994 Volume.12 No. 1 p.70 ~ p.79
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A Clinical Study on Treatment of Myasthenia Gravis
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강성수
박현미/심충섭/권오영/김승현/김주한/김명호
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Abstract
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We studied retrospectively on clinical assessment of treatment in myasthenic patients who visited on our department regularly sine. 1985. They were divided as a group based on therapeutic modalities suchas a thymectomy, steroid therapy, combined
therapy(steroid and thymectomy), plasma exchange. And whole body irradiation. We evaluated clinical effectiveness of these therapeutic modalities and come up with following conclusions.
All therapeutic modalities showed effectiveness. In steroid therapy, thymectomy and the combined therapy. We needed at least 6-24 months for clinical improvement. In thymectomy, prognosis was depend on the number of germinal centers. In whole
body
irradiation, effectiveness was shown at 5th week and continued to 6th to 12th months. We also noted that symptomatic improvement was correlated with decreased lymphocyte counts. The effect of plasma exchange was rapid but only short duration.
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KEYWORD
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